By Scott A. Snyder,Marco Bella,Alexander Dömling,Jon Boyce,Gaelle Blond,Iain Coldham

The swift speed of evolution in domino, or cascade-based ameliorations has revolutionized the perform of chemical synthesis for the construction of usual items, designed molecules, and pharmaceuticals.

"Science of Synthesis: purposes of Domino differences in natural Synthesis" explores the subject completely and systematically, serving because the foundation for useful functions and destiny study. The 2-volume set offers the state-of-the-art when it comes to layout, process, and experimental strategies, resulting in a number of occasions being entire inside of a unmarried response vessel. The content material is geared up by way of the center kind of response used to begin the development, be it a pericyclic response, a metal-mediated transformation, radical chemistry, or an acid-induced cascade between many others.

Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N a number of bonds.

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Applications of Domino Transformations in Organic Synthesis, Volume 2 by Scott A. Snyder,Marco Bella,Alexander Dömling,Jon Boyce,Gaelle Blond,Iain Coldham

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